The aircraft went down into the lake while attempting to land at an airport in Bukoba during stormy weather.
A Precision Air plane has crashed into Lake Victoria in Tanzania while attempting to land at an airport during bad weather.
An official said 26 people had been rescued so far on Sunday, but it was unknown whether there were any deaths.
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Regional commissioner Albert Chalamila said 43 people – including 39 passengers, two pilots and two cabin crew – were on board the plane.
“As we speak, we have managed to rescue 26 people who were taken to our referral hospital,” Chalamila said. “The rescue operation is still ongoing and we are communicating with the pilots.”
The plane departed from the commercial capital, Dar-es-Salaam, and “fell in the Lake Victoria this morning due to storm and heavy rains” in Bukoba.
“We have managed to save quite a number of people,” Kagera province police commander William Mwampaghale told journalists.
“When the aircraft was about 100 metres [328 feet] midair, it encountered problems and bad weather. It was raining and the plane plunged into the water. Everything is under control.”
News reports showed photos of the plane mostly submerged in the lake with only its green and brown-coloured tail visible above the water line.
Speaking to Al Jazeera from Dar-es-Salaam, journalist Faraji Saidi said emergency services were at the scene.